The Fox and Hounds Country Hotel, Devon

The Fox and Hounds Country Hotel is a mid-range, 20-room property occupying a former coaching inn in the heart of the North Devonshire countryside. The setting is genuinely scenic and serene with lush greenery and plenty of wildlife, including fishing on-site. Fox and Hounds, though, may be best known for the Treetops Treehouse; built in a 200-year-old oak tree overlooking the fishing lake, this room option includes luxury-finish interiors, a well-equipped kitchen, a wood-burning fireplace, and a superb copper bathtub.

Tree Houses Hotel Costa Rica

This seven-room eco-resort, a scattering of rustic, sky-high treehouse bungalows, allows guests to live our their Lost Boys fantasies, and keep company with howler monkeys and tree branches. The high-ceilinged treehouses come with wraparound porches and bird feeders that the staff keep supplied with fruit to bring out hummingbirds and howler monkeys. To satisfy guests' grown-up needs, rooms come with conveniences like AC and safes, but modern comforts such as TV or Wi-Fi are nowhere to be found.

Aqua Wellness Resort, Nicaragua

Aqua Wellness Resort is a rustic-luxe retreat with eco-friendly design and lush vegetation (expect to spot wildlife such as howler monkeys and iguanas). The stilted treehouse bungalows are adorned with lots of natural wood; some units include plunge pools and stunning ocean views. The white-sand beach is secluded and beautiful, the restaurant serves simple but tasty local dishes, and group yoga classes on the ocean-view wooden platform are free.

Adventure Suites, New Hampshire

Adventure Suites is a truly one-of-a-kind upscale property. All of the hotel's 17 suites are unique, and completely decked out according to their themes. Each one has a different theme, from a romantic wine cellar to a treehouse for the family. The latter is outfitted with a tree fort and kid-approved decor like license plates, bumper stickers and balloons. There are also plenty of amenities: All suites have hot tubs in assorted shapes and sizes, and the Victorian lobby has a massive DVD library. Make-your-own breakfast and coffee are served in a 1950s-style diner and snacks are provided in the evening.

Portofino Beach Resort, Belize

Owners Jan and Sandra opened this romantic hideaway in 2001, and today it has 16 rooms (many cabana-style units with thatched roofs, including the aptly named Treetop Suite) and one massive option for families and groups. The room decor is a mix of Belizean and Guatemalan textiles and furnishings, and the ambiance is unpretentious (the owners call the vibe "barefoot elegance").